Enhanced external counterpulsation inhibits endothelial apoptosis via modulation of BIRC2 and Apaf-1 genes in porcine hypercholesterolemia
نویسندگان
چکیده
منابع مشابه
Enhanced external counterpulsation promotes growth cytokines-mediated myocardial angiogenesis in a porcine model of hypercholesterolemia.
BACKGROUND Enhanced external counterpulsation (EECP) improves ischemia in patients with refractory angina pectoris, but the mechanism remains unclear. To explore the mechanisms of EECP action, we detected progenitor cells presenting any of the following markers CD34(+), CD29(+), and CD106(+). METHODS Growth cytokines-mediated progenitor cell mobilization and associated angiogenesis potential ...
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Between 25,000 and 75,000 new cases of angina refractory to maximal medical therapy and standard coronary revascularization procedures are diagnosed each year. In addition, heart failure also places an enormous burden on the U.S. health care system, with an estimated economic impact ranging from $20 billion to more than $50 billion per year. The technique of counterpulsation, studied for almost...
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Enhanced external counterpulsation (EECP) is a noninvasive outpatient therapy for the treatment of chronic angina. EECP treatment produces an acute hemodynamic effect that is similar to that produced by the invasive intra-aortic balloon pump. Three sets of cuffs on the upper thigh, lower thigh, and calves of each leg are inflated with compressed air during the diastolic phase of the cardiac cyc...
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In the United States, there are about 17.6 million patients suffer from symptomatic coronary artery disease (CAD), affecting 7.9% of adults ≥ 20 years of age.1 An estimated 10.2 million patients have angina, and 500,000 patients will develop new angina pectoris each year.1 A subset of angina patients are categorized as refractory when symptoms continue despite optimal medical therapy and revasc...
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The development of advanced revascularization techniques has resulted in the growth of a subset of patients with coronary artery disease who are nonrevascularizable and are considered to have refractory angina. Enhanced external counterpulsation (EECP) has been developed for the management of these patients with chronic, refractory disease. Evidence has shown that through improvement of vascula...
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ژورنال
عنوان ژورنال: International Journal of Cardiology
سال: 2014
ISSN: 0167-5273
DOI: 10.1016/j.ijcard.2013.11.033